pbsoli.blogg.se - Myriad foresight carrier screen

Modeled Fetal Risk of Genetic Diseases Identified by Expanded Carrier Screening.

Haque IS, Lazarin GA, Kang HP, Evans EA, Goldberg JD, Wapner RJ.

Systematic design and comparison of expanded carrier screening panels.

Beauchamp KA, Muzzey D, Wong KK, et al.

Validation of an Expanded Carrier Screen that Optimizes Sensitivity via Full-Exon Sequencing and Panel-wide Copy Number Variant Identification.

Open Neural Tube Defects: 1 in 1,000 births 10ġ76 genes associated with serious and prevalent inherited conditions WHO TO SCREENįull-exon sequencing with panel-wide deletion calling.

*when compared to a traditional 23 mutation panel INCIDENCE OF AFFECTED PREGNANCIESĪpproximately 1 in 300 pregnancies are affected by a condition screened by the Myriad Foresight Carrier Screen 1 4,5ģ0% more pregnancies affected with cystic fibrosis* can be identified using Myriad Women’s Health’s testing methodology. Universal carrier screening for cystic fibrosis and spinal muscular atrophy is recommended by American College of Medical Genetics (ACMG) and American College of Obstetricians and Gynecologists. With the best technology available, how well can we identify carriers?įLEXIBLE PANEL CHOICES FOR PERSONALIZED CARE Is this condition common enough to be of value? Is this condition mild? Or is it serious (moderate, severe or profound)?

Thus, we selected 176 genes for the Foresight Carrier Screen. Our experts evaluated >650 genes based on strict criteria in an effort to produce not simply more, but meaningful clinical information. PRIORITIZING CLINICAL SIGNIFICANCE IN PANEL DESIGN Unmatched detection rates for the vast majority of genes on our panel (>99% across ethnicities) means you can trust both positive and negative results. Have the utmost confidence you aren’t missing couples at risk with the highest published at-risk couple detection rate for serious inherited conditions (1 in 22 couples) 1 WE’RE REIMAGINING THE FUTURE OF GENETICS UNMATCHED AT-RISK COUPLE DETECTION That’s why we’ve designed the Foresight Carrier Screen to maximize detection rates for the diseases that matter the most. The goal of carrier screening is to detect couples who are at risk of passing down serious inherited conditions. This means more of your patients will benefit from valuable information that can make a difference in health outcomes for families.

We offer seamless support and services to make it easy to integrate genetic screening into your practice. Myriad Women’s Health pioneered expanded carrier screening and our Myriad Foresight Carrier Screen is systemically designed to maximize the detection of at-risk couples for a pregnancy affected by inherited conditions. Identify more couples at risk of passing down serious inherited, prevalent, and clinically-actionable conditions. MYRIAD FORESIGHT ® CARRIER SCREEN YOUR PARTNER IN PLANNING